Research Title: TARGET
The TARGET Study - Taking Regular breaks from sitting to improve Glycaemic control, blood pressure and Endothelial function in Type 1 diabetes
It is well known that being physically active is important for maintaining good health. However, physical activity can be a significant challenge in the management of T1D.
This study will evaluate whether breaking up sitting time throughout the day with repeated bouts of light-intensity simple body-weight resistance activities results in improved blood glucose control and blood profiles when compared to sitting for prolonged periods without activity breaks. The results of this trial will build on our understanding of the cardiometabolic consequences (i.e. risk of high developing heart disease) of prolonged sitting in individuals with T1D and will help inform the design, implementation and evaluation of intervention strategies in the community to reduce the risk of developing complications associated with diabetes.
- Type 1 diabetes
- Aged 25-65 years
- On an insulin pump for at least 6 months
Find out more details
For more information about this research trial, please contact Ashleigh Homer via email or phone 03 8532 1786
Ethics approval details: This research project has been approved by the Alfred Hospital Ethics Committee (11/18)
Research Title: Hypo-Unaware Closed-Loop Studies
Description: Do you have type 1 diabetes? Would you like to advance research into diabetes management and also have the opportunity to trial the ‘artificial pancreas’ or hybrid closed-loop insulin pump? Have you lost the warning symptoms of a hypo? Have you had at least 1 severe hypo requiring the assistance of another person in the last year? Can you exercise on a stationary bike?
Two studies are currently recruiting at St Vincent’s Hospital Melbourne, targeting people with loss of hypoglycaemia awareness.
- One study explores the performance of the ‘artificial pancreas’ compared with current standard treatment on glucose control, health outcomes and quality of life over a 6-month period. To be eligible, your diabetes can be managed with either injections or an insulin pump.
- The second study explores the performance of the ‘artificial pancreas’ during exercise over a 1-month period.
- Have type 1 diabetes
- Already using an insulin pump
Contact details: please contact Catriona Sims on email
Ethics approval details: These research trials have been approved by the Human Research Ethics Committee at St Vincent’s Hospital Melbourne.
Research Title: FAME-1 Eye Study
Description: Diabetes is the most common cause of adult-onset vision loss. This study is investigating the effect of a tablet that has the potential to reduce eye disease progression and other blood vessel complications in adults with type 1 diabetes and some existent eye changes at St Vincent’s Hospital Melbourne.
- Have type 1 diabetes
- Age 18 years +
- Eye changes (retinopathy)
Download the study flyer attached
Contact details: Sue Kent at St Vincent’s Hospital Melbourne on (03) 9231 2671 or email email@example.com
Ethics approval details: Study has been approved by the Northern Sydney Local Health District Human Ethics Committee
A tablet to improve pancreas function in recently-diagnosed type 1 diabetes
This pilot study at Royal Melbourne Hospital aims to determine if a tablet commonly used to treat type 2 diabetes might also be used to help preserve pancreas function in type 1 diabetes.
Participants need to start the study within 100 days of being diagnosed with type 1 diabetes.
They will receive a daily tablet for six months in addition to their usual treatment, and will visit the research unit on 12 occasions over 9 months.
This study is part of a broader effort to work out how to prevent type 1 diabetes and is being run by Associate Professor John Wentworth and Professor Peter Colman.
Please email firstname.lastname@example.org for further details
This research trial has received ethics approval from Melbourne Hospital Human Research Ethics Committee
ENDIA Study – Finding the causes of Type 1 Diabetes in Early Childhood If you are planning or expecting a baby, or have a baby less than 6 months old, and
- The baby’s mother or father has Type 1 Diabetes, or
- You have another child with Type 1 Diabetes
- Then your family may be eligible to participate in the ENDIA Study
The ENDIA (Environmental Determinants of Islet Autoimmunity) study is finding out what causes Type 1 Diabetes so we can find ways to prevent it. We already know that a child’s genes can increase their risk of developing Type 1 Diabetes. However, Type 1 Diabetes in children is twice as common in Australia as it was 20 years ago. This is because our environment has changed. If we can understand exactly what in the environment is harmful or protective, we can modify the environment to try and prevent Type 1 Diabetes.
This research trial has been reviewed and approved by the Human Research Ethics Committees (HRECs) representing the various sites that are participating in ENDIA.
For more information vist the ENDIA website
, download the flyer
TrialNet studies to prevent other family members getting type 1 diabetes
Type 1 Diabetes TrialNet is a network of 18 clinical centres dedicated to conducting diabetes prevention research and studying intervention therapies for children and adults with newly diagnosed diabetes.
TrialNet in Australia is screening relatives of people with type 1 diabetes to find out if these family members are at risk for developing diabetes. Screening involves a simple blood test for the presence of diabetes-related autoantibodies that may appear years before type 1 diabetes develops.
You may be screened to determine your risk of diabetes if;
are between 1 and 45 years of age and have a first degree blood relative (brother, sister, child, parent) with type 1 diabetes, OR
you are between 1 and 20 years of age and have a second degree blood relative (grandparent, half-brother, or half-sister with type 1 diabetes) with type 1 diabetes.
Relatives of people with type 1 diabetes have about a 5 percent chance of testing positive for autoantibodies associated with diabetes.
There is no cost for the test.
How Will You Benefit From Screening and Further Risk Assessment?
If you learn you are at risk for developing type 1 diabetes, additional tests will be offered to estimate your chances of developing type 1 diabetes. If you qualify, you may have an opportunity to be enrolled in either the Natural History or a prevention study. All research volunteers will be closely monitored for early detection of type 1 diabetes.
You will be part of a research program that may help other people at risk for type 1 diabetes.
For further information about this research visit the TrialNet website
or contact Felicity Healy via email
or phone 03 9342 7063.
Young adults’ experiences of living with type 1 diabetes
Researchers at Curtin University in Western Australia are looking to understand more about young adults’ experiences of living with type 1 diabetes. More specifically, they aim to build an understanding of diabetes self-care behaviours, the impact of mental health and other stressors, and the way people cope with this chronic condition.
If you are:
- Aged 18-35 years and
- Have type 1 diabetes
Curtin University would like to invite you to participate in their online research project. This project requires completion of two online questionnaires 1 week apart. The first questionnaire will take approximately 20 minutes to complete and the second 10 minutes to complete.
Start the survey
Download the information flyer
For further information about this research survey please email
This research study has been approved by Curtin University Human Research Ethics Committee.